These aren't necessarily Mesh Central replacements (one actually uses Mesh Central on the back end) as they're actually RMMs.
The first one that comes to mind, but is the one I haven't used myself yet, is RustDesk. It's completely self hosted, and includes clients for Windows, Linux and MAC. There is a completely free OSS version, and then the licensed versions are very reasonably prices imo. I'm not sure what the differentiators are between the OSS and different paid for versions.
The second one is TacticalRMM. This is the one that uses MeshCentral as the back end remote access, but you never see MeshCentral unless you go looking for it. So depending on what the issues are pushing you away from MeshCentral are, it may be a hard no-go for you. Only provides Windows clients for free, MAC and Linux clients are the only things you pay for.
Both would be way more functionality than what I remember ScreenConnect or Mesh Central making available themselves.
Please do let us know what you end up choosing.