IOPS are the biggest concern really. But without anything like a database which really needs them, RAID 6 might be more than enough. Exchange wouldn't be a big concern as it is not IOPS heavy. RAID 10 is far better tuned for heavy writes, but if reads are the vast majority, RAID 6 will keep right up.

@roguepacket In light of recent events, and I'm leaving it at that, I would be very surprised if I got asked to speak.

Ah I think that I knew that. Although I don't feel like I've seen his alter ego much either.